Senior Investigator Profile

First NameAjit
Award StatusEmeritus
Current PostProfessor of Infectious diseases
DepartmentDepartment of Respiratory Medicine
Telephone0207 594 0883
InstitutionImperial College of Science, Technology and Medicine
NHS TrustImperial College Healthcare NHS Trust
Region NameLondon
Primary Research FieldInfectious Diseases
Secondary Research FieldRespiratory Diseases
BiographyProfessor Lalvani is Chair of Infectious Diseases and Wellcome Senior Clinical Research Fellow at Imperial College London and Honorary Consultant Physician at Imperial College Healthcare NHS Trust. Since his recruitment from Oxford in 2007, his research programme has integrated with Britain’s largest clinical TB service at Imperial, where he leads the multidisciplinary Tuberculosis Research Unit. His research has shaped TB control policy internationally and provided fundamental insights into immunity to intracellular pathogens and the action of TB and malaria vaccines. The NICE-endorsed interferon-gamma blood test (ELISpot, T-SPOT.TB) which he invented and validated is the first advance in diagnosis of latent TB in 100-years and now forms the basis of new national guidelines for TB screening and prevention throughout the world. His ongoing research programme probes the immunologic and genetic factors that shape the natural history and clinical outcomes of TB infection, whilst maintaining a strong translational theme by developing and validating novel biomarkers of infection, disease and treatment response.

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