Senior Investigator Profile

First NameDavid
Award StatusTerm 2
Current PostProfessor of Hepatology, Head of College, Dean of Medicine and Pro Vice Chancellor
DepartmentInstitute of Immunology and Immunotherapy
Telephone0121 4143780
InstitutionUniversity of Birmingham
NHS TrustUniversity Hospitals Birmingham NHS Foundation Trust
Region NameWest Midlands
Primary Research FieldGastroenterology & Hepatology
Secondary Research FieldImmunology - Other
BiographyDavid Adams is Professor of Hepatology and Head of the School of Immunity and Infection at the University of Birmingham. He is Director of translational research in the Birmingham MRC Centre for Immune Regulation and director of the Birmingham NIHR Biomedical Research Unit for Liver disease. His clinical interests are transplant hepatology and autoimmune liver disease. After initial training in hepatology in Birmingham he continued his immunology training with Dr Stephen Shaw at the Experimental Immunology Branch of the National Cancer Institute, Bethesda, USA before being appointed to the Chair of hepatology in Birmingham in 1997. He is a trustee of the charity PSC Support which provides information and support and lobbies on behalf of patients with the liver disease primary sclerosing cholangitis. He has a long-standing interest in mentoring clinical academics and chairs the Academy of Medical Sciences mentoring and outreach working group and served as an MRS/AMS Clinical Research Champion. His lab work on immune regulation in the liver with a particular interest in leucocyte trafficking. They demonstrated the role of specific adhesion molecules and chemokines and proposed a novel paradigm in which aberrant lymphocyte trafficking explains the hepatic manifestations of inflammatory bowel disease. Knowledge of the molecular mechanisms that regulate leucocyte trafficking to the liver is now being used to develop immune and cellular therapies for liver disease though the Birmingham NIHR BRU in Liver Disease (

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